Evidence map›Paper›PMID 41998517›Full record

ArticleBasic and clinical andrology2026

Microscopic ligation combined with shunt procedure versus microsurgical varicocelectomy for nutcracker syndrome and left varicocele: a randomized controlled trial.

Ke Dou, Xinchen Zeng, Qi Yang, Yutao Li, Lei Wang, Tao Song, Juncheng Yao

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Article in Basic and clinical andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ke Dou *Department of Urology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610041, Sichuan, China. doczxc@alu.uestc.edu.cn.
Xinchen Zeng *Reproductive Medicine Center, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, 621000, Sichuan, China.
Qi YangDepartment of Urology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610041, Sichuan, China.
Yutao LiDepartment of Assisted Reproduction Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No.32, Section 2, West 1 Ring Road, Qingyang District, Chengdu, 610041, Sichuan, China.
Lei WangDepartment of Reproduction and Infertility, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610073, China.
Tao SongDepartment of Urology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610041, Sichuan, China.
Juncheng YaoDepartment of Assisted Reproduction Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No.32, Section 2, West 1 Ring Road, Qingyang District, Chengdu, 610041, Sichuan, China.

Funding

Key Research and Development Project of the Science and Technology Department of Sichuan Province 23ZDYF1464
6 · The paper itself

Abstract

backgroundThis study is to evaluate the safety and efficacy of a novel microsurgical approach (Microsurgical Spermatico-Inferior Epigastric Vein Anastomosis with Selective Venous Disconnection, MSEA-SVD) compared to conventional Microsurgical Varicocelectomy approach in patients with Nutcracker Syndrome and left-sided varicocele. This single-center, randomized controlled trial enrolled 50 patients (25 per group) diagnosed with Nutcracker Syndrome and left-sided varicocele. Group A underwent MSEA-SVD, while Group B received Microsurgical Varicocelectomy. The primary outcomes included semen quality, renal vein hemodynamics, and varicocele recurrence. Follow-up assessments were conducted at 1, 3, and 6 months postoperatively using color Doppler ultrasound and semen analysis. Statistical comparisons were performed using IBM SPSS 27.0.

resultsMSEA-SVD achieves superior outcomes in semen quality and renal vein decompression compared to Microsurgical Varicocelectomy but requires a longer surgery time and hospitalization.

conclusionsWith careful patient selection, MSEA-SVD may become a preferred approach for managing Nutcracker Syndrome-related varicocele.

Indexed as

AnastomosisMicrosurgeryNutcracker syndromeRenal veinSemen qualityVaricocele

Identifiers

PMID41998517
PMCPMC13088607

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.