ArticleBMC cardiovascular disorders2026
Association between blood urea nitrogen to albumin ratio and 28-day mortality of acute heart failure in intensive care unit: analysis based on MIMIC-IV database.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAcute heart failure (AHF) is a common complication in critically ill patients. The purpose of this study was to investigate the relationship between blood urea nitrogen to albumin ratio (BAR) and poor prognosis of AHF in the Intensive Care Unit (ICU).
methodsAHF patients were selected from the MIMIC-IV 2.2 database and data were extracted. Boruta algorithm was used for feature selection. Cox regression analysis, restricted cubic spline (RCS) analysis and Kaplan-Meier survival curve were used to evaluate the association between BAR and mortality. Receiver Operating Characteristic (ROC) was used to evaluate the diagnostic accuracy and subgroup analysis was performed to evaluate the universality of the results.
resultsA total of 671 patients were included in the database, and Boruta analysis identified BAR as an important clinical feature. BAR, whether as a continuous variable or grouped, suggests that BAR is a predictor of poor prognosis of AHF, and a higher level indicates a poor prognosis. The RCS model reveals the nonlinear relationship between BAR and mortality. The Area Under Curve (AUC) and 95% CI of BAR in predicting 28-day mortality and 90-day mortality were 0.645 (0.588–0.699) and 0.643 (0.593–0.692), respectively. Subgroup analysis showed that age, gender, Continuous Renal Replacement Therapy (CRRT) and scoring system were the factors affecting the predictive value.
conclusionBAR may have potential value in predicting the mortality of patients with AHF in ICU, supporting the early use of risk assessment. However, further studies are needed to confirm this result.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.