ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Pediatric idiopathic intracranial hypertension: prognostic value of obesity and cerebrospinal fluid pressure.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPediatric idiopathic intracranial hypertension (IIH) is a rare but potentially vision-threatening disorder.
objectiveThis study aimed to evaluate the clinical characteristics, prognostic indicators, and outcomes in pediatric IIH, with a specific focus on the effects of obesity and cerebrospinal fluid (CSF) opening pressure.
methodsTwenty-six children under 18 years of age, diagnosed according to the revised Friedman criteria, were retrospectively analyzed. Clinical, ophthalmologic, and neuroimaging data were collected. Correlation and logistic regression analyses were performed to determine predictors of residual visual deficit.
resultsThe mean age was 11.2 ± 3.4 years, and 53.8% of the patients were female. Overweight and obesity were observed in 34.6% and 19.2% of cases, respectively. Headache (80.7%) and papilledema (76%) were the most common findings. The mean CSF opening pressure was 335 ± 85 mmH₂O. A significant correlation was found between CSF pressure and papilledema grade (r = 0.41, p = 0.04). In the exploratory multivariable logistic regression analysis, elevated CSF opening pressure was associated with residual visual deficit (OR 3.2, 95% CI 1.1-9.1, p = 0.04).
conclusionElevated CSF opening pressure and obesity appear to be associated with visual outcomes in pediatric IIH. Early recognition and multidisciplinary management may help prevent irreversible visual loss and improve long-term prognosis.
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