Evidence map›Paper›PMID 41998358›Full record

ArticleNature structural & molecular biology2026

Calcium dependent activation of the TMEM16F scramblase and ion channel.

Zhang Feng, Omar E Alvarenga, Eleonora Di Zanni, Sangyun Lee, George Khelashvili, Alessio Accardi

Abstract read
In one paragraph

Article in Nature structural & molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Molecular mechanisms of Kir channel gating.Biochemical Society transactions · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhang Feng *Department of Anesthesiology, Weill Cornell Medical College, Anesthesiology, New York, NY, USA.ORCID http://orcid.org/0000-0002-5623-7416
Omar E Alvarenga *Department of Anesthesiology, Weill Cornell Medical College, Anesthesiology, New York, NY, USA.
Eleonora Di ZanniDepartment of Anesthesiology, Weill Cornell Medical College, Anesthesiology, New York, NY, USA.
Sangyun LeeDepartment of Anesthesiology, Weill Cornell Medical College, Anesthesiology, New York, NY, USA.ORCID http://orcid.org/0000-0001-6272-4678
George KhelashviliDepartment of Systems and Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA.ORCID http://orcid.org/0000-0001-7235-8579
Alessio AccardiDepartment of Anesthesiology, Weill Cornell Medical College, Anesthesiology, New York, NY, USA. ala2022@med.cornell.edu.ORCID http://orcid.org/0000-0002-6584-0102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitous transmembrane protein 16F (TMEM16F) Ca

Indexed as

AnoctaminsCalciumPhospholipid Transfer ProteinsAnimalsCryoelectron MicroscopyHumansLiposomesMolecular Dynamics SimulationProtein ConformationANO6 protein, humanAnoctaminsCalciumLiposomesPhospholipid Transfer Proteins

Identifiers

PMID41998358
PMCPMC13095661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.