ArticleCommunications medicine2026
Antiviral CD4
Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Adaptive-like NK cell responses to influenza correlate with humoral immunity and are influenced by age and sex.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update ofAntiviral CD42025
Authors and funding
10 authors.
Funding
Abstract
backgroundRecent influenza vaccine formulations have improved the magnitude of B-cell antibody responses in older adults; however, older adults remain significantly at risk for severe influenza-related illness. Although antibodies are an important metric of vaccine effectiveness, they only represent one aspect of the immune response.
methodsIn this study, we combined in vitro and ex vivo immune assays with human samples to investigate B cell, CD4
resultsWe found that older adults mounted antibody titers equivalent to those of younger adults but had fewer influenza-reactive CD4
conclusionsThese data suggest that with aging, transcriptional programming alterations in myeloid and T cells contribute to reduced antiviral responses, and formulating vaccines tailored to cellular immune responses is necessary to improve outcomes in older adults.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.