Evidence map›Paper›PMID 41998108›Full record

ArticleScientific reports2026

The SPECT/CT radiomics-based classification of skeletal metastases and benign bone lesions.

So Eun Choi, Ji-Young Kim, So Hyun Ahn, Hai-Jeon Yoon

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

So Eun ChoiDepartment of Computational Medicine, Ewha Womans University, College of Medicine, Seoul, Korea.ORCID http://orcid.org/0009-0001-0702-3219
Ji-Young KimDepartment of Nuclear Medicine, Ewha Womans University, College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0002-3226-2991
So Hyun Ahn *Department of Biomedical Engineering, Ewha Womans University, College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0002-0116-3325
Hai-Jeon Yoon *Department of Computational Medicine, Ewha Womans University, College of Medicine, Seoul, Korea. haijeon.yoon@ewha.ac.kr.ORCID http://orcid.org/0000-0001-8752-6280

Funding

Korea government(MSIT) RS-2024-00453521Korea Health Technology RS-2025-02214254National Research Foundation of Korea NRF-2020R1A5A2019210
6 · The paper itself

Abstract

Hybrid Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) improves lesion localization and diagnostic accuracy in detecting skeletal metastases. However, interpretation based on standardized uptake value (SUV) remains suboptimal due to overlapping uptake between benign and malignant lesions. Radiomics quantifies intralesional heterogeneity and may overcome SUV limitations. This study aimed to evaluate whether integrating SPECT/CT radiomics with SUV improves differentiation between skeletal metastases and benign bone lesions. Sixty-three patients who underwent SPECT/CT between September 2021 and March 2024 at Ewha Mokdong Hospital were included. Benign and metastatic lesions were classified based on histopathology or imaging follow-up. Four classification models were developed based on features: (1) SUV

Indexed as

Bone NeoplasmsRadiomicsSingle Photon Emission Computed Tomography Computed TomographyAdultAgedFemaleHumansMaleMiddle AgedSupport Vector MachineTomography, Emission-Computed, Single-Photon

Identifiers

PMID41998108
PMCPMC13266059

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.