Evidence map›Paper›PMID 41998051›Full record

ArticleScientific reports2026

Development of value-added goat meat spread fortified with nano calcium.

M Raziuddin, R Narendra Babu, V Appa Rao, R Ramani, A V Bhosale, C Vasanthi, Shaikh Adil

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M RaziuddinDepartment of Livestock Products Technology, College of Veterinary and Animal Sciences, MAFSU, Udgir, M.S, 413517, India. dr_razi@rediffmail.com.
R Narendra BabuDepartment of Livestock Products Technology (Meat Science), Madras Veterinary College, TANUVAS, Chennai, TN, 600007, India.
V Appa RaoTANUVAS, Chennai, TN, 600007, India.
R RamaniDepartment of Livestock Products Technology (Meat Science), Madras Veterinary College, TANUVAS, Chennai, TN, 600007, India.
A V BhosaleDepartment of Veterinary Microbiology, College of Veterinary and Animal Sciences, MAFSU, Udgir, M.S, 413517, India.
C VasanthiDepartment of Livestock Products Technology (Meat Science), Madras Veterinary College, TANUVAS, Chennai, TN, 600007, India.
Shaikh AdilDepartment of Dairy Technology, Parul Institute of Technology, Parul University, Vadodara, Gujarat, 391760, India. shaikh.adil23773@paruluniversity.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food-grade calcium carbonate nanoparticles were synthesized using a simple top-down ball-milling approach that produced a 90% yield in 3 h. Dynamic light scattering, scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDAX) were employed to characterize the nanoparticles. The size of nano-calcium carbonate was 17.4-38.8 nm and observed zeta potential of - 33.1 mV revealed good colloidal stability. The cytotoxicity study was performed using the African monkey kidney cell line (Vero) after 24, 48, and 72 h of incubation. The t-test of cell viability revealed highly significant (P ≤ 0.01) differences between nano and micro-calcium carbonate across concentrations at 24, 48, and 72 h intervals. After analyzing the nanoparticles, goat meat spread was treated with three levels of nano calcium carbonate (0.75, 1.5 and 2.25 g). As the concentration increased, the pH increased non-significantly, and resulted in a highly significant (P ≤ 0.01) increase in its lightness (L*). The addition of nano calcium carbonate negatively affected sensory scores at higher concentration. An in vitro digestion study showed that soluble calcium was significantly (P ≤ 0.05) greater in the treatment involving nano calcium carbonate than in the control and micro calcium carbonate. Overall, the study demonstrates improved calcium solubility and bioavailability, supporting the potential of nano-calcium carbonate as a functional calcium delivery ingredient in meat-based products.

Indexed as

CalciumCalcium CarbonateMeatNanoparticlesAnimalsCell SurvivalChlorocebus aethiopsGoatsParticle SizeSpectroscopy, Fourier Transform InfraredVero CellsX-Ray DiffractionCalciumCalcium CarbonateGoat meat spreadIn vitro studyNano calcium carbonateParticle sizeZeta potential

Identifiers

PMID41998051
PMCPMC13249862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.