Evidence map›Paper›PMID 41997491›Full record

ArticleThe Journal of nutrition2026

Diet Quality, Physical Activity, and Epigenetic Aging in the Finnish Working-Age Population.

Ida Autio, Aino Saarinen, Saara Marttila, Emma Raitoharju, Pashupati P Mishra, Katja Pahkala, Satu Männistö, Nina Mononen, Mika Kähönen, Mikael Fogelholm and 6 more

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PubMed Full text at PMC Publisher
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Article in The Journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ida AutioDepartment of Psychology, Faculty of Medicine, University of Helsinki, Finland.
Aino SaarinenDepartment of Psychology, Faculty of Medicine, University of Helsinki, Finland. Electronic address: aino.i.saarinen@helsinki.fi.
Saara MarttilaMolecular Epidemiology, Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Gerontology Research Center, Tampere University, Tampere, Finland; Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland.
Emma RaitoharjuMolecular Epidemiology, Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Pashupati P MishraDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Katja PahkalaResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland; Paavo Nurmi Centre and Unit for Health and Physical Activity, University of Turku, Turku, Finland.
Satu MännistöNational Institute for Health and Welfare, Helsinki, Finland.
Nina MononenTampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland; Department of Clinical Chemistry, Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mikael FogelholmDepartment of Food and Nutrition, University of Helsinki, Helsinki, Finland.
Tuija TammelinLikes, School of Health and Social Studies, Jamk University of Applied Sciences, Jyväskylä, Finland.
Suvi RovioResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland; Department of Public Health, University of Turku, Turku University Hospital, Turku, Finland.
Liisa Keltikangas-JärvinenDepartment of Psychology, Faculty of Medicine, University of Helsinki, Finland.
Jorma ViikariDepartment of Medicine, University of Turku and Division of Medicine, Turku University Hospital.
Olli RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of diet in epigenetic aging over long follow-up periods and the possible moderating role of physical activity have remained unclear.

objectivesWe examined: 1) whether dietary habits over follow-ups of 17-32 y are associated with the level or change of epigenetic aging over a 7-y follow-up, and 2) whether physical activity moderates these associations.

methodsThe prospective population-based Young Finns Study data (n = 1039) were used. Epigenetic aging was measured in 2011 and 2018 using PhenoAge and GrimAge age deviation (AgeDev

resultsMore favorable scores in: 1) all diet indices except Dietscore were associated with decelerated AgeDev

conclusionsHealthier eating over the follow-up was associated with decelerated epigenetic changes across different diet indices. In terms of biological aging, having a healthy diet may be especially crucial for those with low levels of physical activity.

Indexed as

AgingDietEpigenesis, GeneticExerciseAdolescentAdultFeeding BehaviorFemaleFinlandHumansMaleProspective StudiesYoung Adultbiological agingdiet healthinessdiet qualityepigenetic clockMediterranean dietphysical activity

Identifiers

PMID41997491
PMCPMC13279305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.