SynthesisBrazilian journal of physical therapy
Effectiveness of different exercise modalities in Heart Failure with preserved Ejection Fraction. A systematic review with network meta-analysis.
Synthesis in Brazilian journal of physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe study aimed to compare the effectiveness of various exercise modalities in improving exercise performance, echocardiographic parameters and quality of life in patients with heart failure with preserved ejection fraction.
methodsA systematic review over 7 databases was conducted up to May 2024. Randomised controlled trials analysing the efficacy of any exercise modality in isolation were included. For each variable, a Frequentist and Bayesian Network Meta-Analysis were conducted. Mean differences between groups with 95% confidence and credible intervals were calculated for each outcome. Quality of the evidence was assessed with GRADE, being very low for every outcome.
results12 RCTs were included, providing data from 602 patients. The Frequentist model showed effectiveness for: CT on peak VO2, VO2 at ventilatory threshold (VT) and E/é ratio; high-intensity interval training (HIIT) on peak VO2, VE/VCO2 slope, cardiopulmonary exercise testing (CPET) time and E/é; inspiratory muscle training (IMT) on peak VO2, VE/VCO2 slope, RER and 6-minute walking test (6MWT); moderate-intensity aerobic training (MIAT) on peak VO2, CPET time, peak power output (PPO), 6MWT and E/é ratio; and Tai Chi on peak VO2. The Bayesian model only supports these findings for CT on peak VO2; IMT on peak VO2; MIAT on CPET time, PPO, and 6MWT; and Tai Chi on peak VO2.
conclusionsConsidering both models, the evidence, albeit of very low quality, supports the effectiveness of various exercise modalities except HIIT in exercise capacity parameters (peak VO2, CPET time, PPO and 6MWT). There is an effect over VO2 at VT, VE/VCO2 slope, RER, LVEF, E/é and MLHFQ, but only supported by the Frequentist model. PROSPERO REGISTRATION NUMBER: CRD42024560028.
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