ArticleActa psychologica2026
Invisible pain: Sex/gender differences in pain-related stigma.
Article in Acta psychologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveStigma is associated with worse pain, function, and negative affect (i.e., health outcomes). It is unclear whether the well-documented sex/gender disparities in health outcomes extend to stigma and whether relationships between stigma and health outcomes differ by sex/gender. This study examined (1) sex/gender differences in pain, mental health, and opioid stigma (i.e., health-related stigma); (2) the relationships between health-related stigma and health outcomes; and (3) whether sex/gender moderates relationships between health-related stigma and health outcomes.
designThis is a secondary analysis of cross-sectional baseline data from an RCT of multimodal treatment for adults with CLBP and negative affect.
settingThree academic medical centers across the Midwest and Northeast.
methods261 adults completed measures of pain, mental health, and opioid medication stigma, pain, function, and negative affect upon enrollment. We compared health-related stigma and health outcomes across cisgender men and women, examined correlations between stigma and health outcomes, and explored sex/gender as a potential moderator of the relationship between stigma and health outcomes.
resultsChronic pain stigma was associated with greater pain, poorer function, and greater (i.e., worse) negative affect, whereas mental health and opioid stigma were primarily associated with greater negative affect. There were no sex/gender differences in stigma or health outcomes nor did sex/gender moderate the relationships between stigma and outcomes.
conclusionsStigma interventions may improving health outcomes among adults with CLBP and may be similarly important for men and women.
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