Evidence map›Paper›PMID 41996531›Full record

ArticleJournal of medicinal chemistry2026

Stereochemical Aspects in the Context of the Structure-Activity Relationship of Chlorido[

Astrid Dagmar Bernkop-Schnürch, Stefanie Schwarz, Philipp Rigo, Daniel Leitner, Mostafa Alilou, Martin Hermann, Michael Seidl, Magnus Andre Kiechle, Sofie Hanifle, Stephan Hohloch and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Astrid Dagmar Bernkop-SchnürchDepartment of Pharmaceutical Chemistry, Institute of Pharmacy, CCB─Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.ORCID 0009-0001-2632-8739
Stefanie SchwarzDepartment of Internal Medicine V (Hematology and Oncology), Immunobiology and Stem Cell Laboratory, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Philipp RigoDepartment of Pharmaceutical Chemistry, Institute of Pharmacy, CCB─Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Daniel LeitnerDepartment of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Mostafa AlilouDepartment of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Martin HermannDepartment of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Michael SeidlDepartment of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Magnus Andre KiechleDepartment of Pharmaceutical Technology, Institute of Pharmacy, CCB─Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Sofie HanifleDepartment of Internal Medicine V (Hematology and Oncology), Immunobiology and Stem Cell Laboratory, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Stephan HohlochDepartment of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.ORCID 0000-0002-5353-0801
Brigitte KircherDepartment of Internal Medicine V (Hematology and Oncology), Immunobiology and Stem Cell Laboratory, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID 0000-0003-1624-2664
Ronald GustDepartment of Pharmaceutical Chemistry, Institute of Pharmacy, CCB─Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.ORCID 0000-0002-0427-4012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this structure-activity relationship study, chlorido[

Indexed as

Antineoplastic AgentsCoordination ComplexesFerric CompoundsCell Line, TumorFerroptosisHumansOxidative StressStereoisomerismStructure-Activity RelationshipAntineoplastic AgentsCoordination ComplexesFerric Compounds

Identifiers

PMID41996531
PMCPMC13181772

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.