ArticleScience advances2026
A panoramic view of the expression and function of the Doublesex/DMRT gene family in
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Sexual dimorphism in the nervous system: Three principles from the nematode C.elegans.Current opinion in neurobiology · 2026Review
- Expression atlas of Dmrt genes across sex and development in the mouse brain: functional insights from the olfactory system.Biology of sex differences · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Throughout the animal kingdom, sex determination and sexual differentiation are orchestrated by a strikingly diverse set of regulatory factors. The only type of molecules consistently deployed during sexual differentiation are members of the Doublesex/MAB-3-related transcription factor (DMRT) family. Although each animal genome codes for a multitude of DMRT family members, in no species has the full array of DMRT genes been comprehensively analyzed across the entire animal, in all sexes and throughout development. Hence, the extent of deployment of DMRT genes in sexual differentiation remains unknown. We describe here a genome- and nervous system-wide expression and functional analysis of all members of the DMRT gene family. Leveraging genome-engineered reporter alleles of all 10 DMRT genes of the nematode
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