Evidence map›Paper›PMID 41996301›Full record

ArticleSexually transmitted diseases2026

Assessing the Impact of an Sexually Transmitted Infections Nurse on the Delivery of Sexually Transmitted Infections/Human Immunodeficiency Virus Services in an Inner-City Emergency Department Using a Human Immunodeficiency Virus/Syphilis Point-of-Care Test During a Syphilis Outbreak in Alberta, Canada.

Jennifer Gratrix, Noel Ives, Cari Egan, Carla Vetland, Garret Meyer, Shannon Harrington, Rob Wittmeier, Alkarim Velji, Byron Berenger, Sean Rourke and 3 more

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer GratrixFrom the STI Services, Communicable Disease Control, Primary Care Alberta, Edmonton.
Noel IvesFrom the STI Services, Communicable Disease Control, Primary Care Alberta, Edmonton.
Cari EganFrom the STI Services, Communicable Disease Control, Primary Care Alberta, Edmonton.
Carla VetlandHealth Systems Knowledge and Evaluation, Provincial Clinical Excellence, Acute Care Alberta, Calgary.
Garret MeyerFrom the STI Services, Communicable Disease Control, Primary Care Alberta, Edmonton.
Shannon HarringtonEmergency Department, Royal Alexandra Hospital, Alberta Health Services, Edmonton.
Rob WittmeierEmergency Department, Royal Alexandra Hospital, Alberta Health Services, Edmonton.
Alkarim VeljiEmergency Department, Royal Alexandra Hospital, Alberta Health Services, Edmonton.
Byron BerengerProvincial Laboratory for Public Health, Alberta Precision Laboratories, Calgary, Alberta.
Sean RourkeMAP Centre for Urban Health Solutions, St. Michaels' Hospital (Unity Health Toronto), Toronto, Ontario.
Kevin FonsecaProvincial Laboratory for Public Health, Alberta Precision Laboratories, Calgary, Alberta.
Ameeta E SinghDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Syphilis and HIV Point-of-Care Testing in Acute Care and Community (SHACC) Team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA sexually transmitted infection (STI) nurse was embedded in an emergency department (ED) to support implementation of human immunodeficiency virus (HIV) and syphilis point-of-care testing (POCT).

methodsOutcomes were compared between two time periods: (1) routine care and (2) the introduction of HIV/syphilis treponemal POCT and an STI nurse. POCT and standard serology were offered to eligible people with HIV or syphilis as a differential diagnosis, who were at risk of loss to follow-up, or who were pregnant without prenatal screening. Testing volumes, rates of new diagnoses, and treatment initiation between the time periods were compared using Chi-square or Fisher exact tests for categorical variables and Mann-Whitney U test for continuous variables.

resultsA total of 2689 visits included HIV or syphilis testing, with serology more common in the postintervention period than in the preintervention period (HIV: 91.0% vs 81.4%, P < 0.001; syphilis: 86.4% vs 77.8%, P < 0.001). Rates of newly diagnosed syphilis increased slightly in the postintervention period (0.12% vs 0.09%; P = 0.07), with more same-visit syphilis treatment initiated in the postintervention period (54.1% vs 17.6%, P < 0.001). The number of newly diagnosed syphilis cases was 46.7% higher in STI registered nurse (RN) visits (n = 44) than ED Staff-only (n = 30), all new cases of HIV were found during STI RN visits, and POCT was ordered in 78.4% (n = 472) of the STI RN visits as compared with 15.6% (n = 178) of visits with ED staff-only ( P < 0.001).

conclusionsAn STI nurse in an urban ED contributed to the increased HIV and syphilis testing rates, and same-visit syphilis treatment initiation.

Indexed as

Disease OutbreaksEmergency Service, HospitalHIV InfectionsPoint-of-Care SystemsPoint-of-Care TestingSexually Transmitted DiseasesSyphilisAdultAlbertaFemaleHumansMaleMiddle AgedPregnancyRapid Diagnostic TestsSyphilis Serodiagnosis

Identifiers

PMID41996301
PMCPMC13326927

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.