Evidence map›Paper›PMID 41995662›Full record

ArticleJACC. Case reports2026

Borderline Arrhythmogenic Cardiomyopathy in an Athlete: Exercise Testing May Support Clinical Decision-Making.

Simon Wernhart, Martin Halle, Mark J Haykowsky, Satyam Sarma

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simon WernhartDepartment for Preventive Sports Medicine and Sports Cardiology, TUM School of Medicine and Health, TUM University Hospital, Technical University of Munich (TUM), Munich, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. Electronic address: simon.wernhart@mri.tum.de.
Martin HalleDepartment for Preventive Sports Medicine and Sports Cardiology, TUM School of Medicine and Health, TUM University Hospital, Technical University of Munich (TUM), Munich, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Mark J HaykowskyIntegrated Cardiovascular and Exercise Physiology and Rehabilitation (iCARE) Laboratory, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Hochgebirgsklinik, Davos, Switzerland.
Satyam SarmaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArrhythmogenic cardiomyopathy (ACM) bears a considerable risk of malignant arrhythmias and heart failure, but diagnosis in athletes can be challenging. CASE SUMMARY: We present a male 52-year-old long-distance runner with palpitations, a dilated right ventricle with apical akinesia, nonsustained ventricular tachycardia, and negative genetic testing. We performed combined stress echocardiography and cardiopulmonary exercise testing showing blunted exercise response and a decrease in right ventricular strain during exercise. Although the modified task force criteria were not met, a diagnosis of ACM based on impaired exercise response was made, and termination of high-intensity endurance and restriction to 150 minutes/wk of moderate-intensity training was recommended. DISCUSSION: The modified task force criteria are recommended for clinical decision-making, but clinical uncertainties remain in gene-elusive cases. Stress testing may complement current guidelines to unmask underlying cardiomyopathy. TAKE-HOME MESSAGE: Stress testing should be considered in athletes showing borderline features of ACM.

Indexed as

arrhythmogenic cardiomyopathyathleteexercise stress testing

Identifiers

PMID41995662
PMCPMC13379855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.