Evidence map›Paper›PMID 41995576›Full record

ArticleMedicine2026

Impact of nonalcoholic fatty liver disease severity on community-acquired pneumonia in children and adolescents aged 6 to 17 years: A retrospective CT-based study.

Hanwen Shi, Ruilin Gu, Huijuan Tu, Jianchun Tu, Guang Yang, Juntao Cao

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanwen ShiDepartment of Radiology, Kunshan Integrated TCM and Western Medicine Hospital, Kunshan, Jiangsu, China.
Ruilin GuDepartment of Radiology, Kunshan Hospital of Chinese Medicine, Kunshan, Jiangsu, China.
Huijuan TuDepartment of Radiology, Kunshan Hospital of Chinese Medicine, Kunshan, Jiangsu, China.
Jianchun TuDepartment of Radiology, Kunshan Hospital of Chinese Medicine, Kunshan, Jiangsu, China.
Guang YangDepartment of Radiology, Kunshan Integrated TCM and Western Medicine Hospital, Kunshan, Jiangsu, China.
Juntao CaoDepartment of Radiology, Kunshan Hospital of Chinese Medicine, Kunshan, Jiangsu, China.ORCID 0000-0002-8379-5317

Funding

Suzhou Applied Basic Research Technology Innovation Project SYWD2024076
6 · The paper itself

Abstract

This study aims to investigate the potential impact of nonalcoholic fatty liver disease (NAFLD) on the risk or severity of community-acquired pneumonia (CAP) in children and adolescents aged 6 to 17 years. Non-contrast chest computed tomography (CT) scans and laboratory data from patients aged 6 to 17 years with respiratory symptoms or fever between July and December 2023 were retrospectively analyzed. NAFLD and its severity were diagnosed based on a liver-spleen CT value ratio. The incidence and distribution of NAFLD across each age group were calculated. Abdominal circumference was measured using CT with specialized software. Chest CT scores quantified the severity of CAP, while inflammatory indices assessed positive C-reactive protein levels and white blood cell counts. Patients with NAFLD were assigned to the observation group, with non-NAFLD patients matched by age and sex served as the control group in a 1:1 ratio. One-way analysis of variance and independent sample rank-sum tests were used to analyze differences in chest CT scores, abdominal circumference, and inflammatory indices. Among 4740 eligible cases, the incidence of NAFLD increased with age, with an overall rate of 5.30%, and was more common in boys. The NAFLD group showed significantly higher abdominal circumference and inflammatory indices than those of the non-NAFLD group (P < .05). There were no significant intergroup differences in chest CT scores or sex (all P > .05). The chest CT score, proportion of males, and abdominal circumference were significantly higher in the moderate-to-severe NAFLD group than that in the mild NAFLD group (all P < .05). No significant intergroup differences were observed in age or inflammatory indices (all P > .05). Patients with moderate-to-severe NAFLD had higher chest CT scores than those with mild NAFLD. Moderate-to-severe NAFLD was associated with an increased risk or severity of CAP in children and adolescents aged 6 to 17 years.

Indexed as

Community-Acquired PneumoniaNon-alcoholic Fatty Liver DiseaseAdolescentChildCommunity-Acquired InfectionsFemaleHumansIncidenceMaleRetrospective StudiesRisk FactorsSeverity of Illness IndexTomography, X-Ray Computedacquired pneumoniaalcoholic fatty liver diseasecommunitycomputed tomographynon

Identifiers

PMID41995576
PMCPMC13095340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.