Evidence map›Paper›PMID 41995515›Full record

ArticleMedicine2026

Publication trends of dexmedetomidine and perioperative cognitive dysfunction: A bibliometric analysis from 1995 to 2024.

Difei Zhou, Lan Yang, Shuai Miao, Xin Zhang

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Difei ZhouDepartment of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Lan YangDepartment of Critical Care Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Shuai MiaoDepartment of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Xin ZhangDepartment of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.ORCID 0000-0003-2675-8197

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDexmedetomidine (Dex) has shown potential in mitigating perioperative cognitive dysfunction (POCD). This study aimed to systematically evaluate the research hotspots and development trends in Dex and POCD using bibliometric analysis.

methodsA systematic search was conducted on the Web of Science Core Collection database to identify publications related to Dex and POCD from 1995 to 2024. Bibliometric analysis was performed using VOSviewer (V 1.6.20), CiteSpace (V 6.3.R1), and R V4.3.3.

resultsA total of 585 articles on Dex and POCD between 1995 and 2024 were analyzed. These articles involved 1688 authors from 1857 institutions across 140 countries or regions, published in 240 journals, and citing 12,881 sources. The annual growth rate of publications in this field was 16.21%, with a peak of 91 articles in 2021. China led in the number of articles (n = 379), multiple country publications (MCP = 29), and total citations = 4989). The USA ranked second with 74 articles, 18 MCPs, and 2608 citations, followed by South Korea with 29 articles and 533 citations. Harvard University published the most articles (n = 51). Wang Dong-Xin was the most influential author, with an h-index of 7. Anesthesiology led the high-impact journals with an H-index of 11. The keyword analysis identified "neuroinflammation," "risk," "injury," and "efficacy" as the latest research themes.

conclusionThis bibliometric analysis provides a comprehensive overview of the research trends regarding Dex and POCD. Future research should continue to explore the mechanisms, efficacy, and safety of Dex in preventing POCD.

Indexed as

BibliometricsCognitive DysfunctionDexmedetomidineHumansDexmedetomidinebibliometricsdexmedetomidineperioperative cognitive dysfunctionvisualization trendsWeb of Science Core Collection

Identifiers

PMID41995515
PMCPMC13095259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.