ArticleJournal of feline medicine and surgery2026
Feline tarsal tumours: histological spectrum, risk factors and prognostic insights.
Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
ObjectivesTarsal tumours are rare, but previous reports suggest a predilection for round cell tumours (RCTs) and soft tissue sarcomas (STSs) in this region. This study aimed to determine the proportion of RCTs among feline tarsal neoplasms, refine classification through histological revision and immunohistochemistry (IHC), assess potential risk factors and evaluate clinical outcomes based on tumour histotypes.MethodsA retrospective analysis of feline tarsal neoplasms diagnosed between 2010 and 2024 was conducted. Signalment, history, treatment and outcomes were collected for RCTs and STSs. All RCTs underwent histological review and IHC (CD3, CD20, CD79a, MUM-1, CD18, IBA-1, E-CAD). A diagnostic algorithm was applied to support the diagnostic process.ResultsA total of 34 cases were included: 18 RCTs and 16 STSs. In 39% of RCTs, the initial histotype was undetermined. After IHC and application of the diagnostic algorithm, 50% of cases were reclassified: seven plasma cell tumours, four progressive histiocytosis, three lymphomas, two histiocytic sarcomas and two undifferentiated RCTs. Male sex, older age and prior tarsal trauma were significantly associated with RCTs (
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