Evidence map›Paper›PMID 41994845›Full record

ArticleLeukemia research reports2026

Therapeutic outcomes of acute promyelocytic leukemia in children.

Sirine Chatti, Emna Azza, Marwa Bahri, Roua Hsasna, Yosr Ben Abdennebi, Lamia Aissaoui

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Article in Leukemia research reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sirine ChattiHôpital Aziza Othmana Tunis, Tunis, Tunisia.
Emna AzzaHôpital Aziza Othmana Tunis, Tunis, Tunisia.
Marwa BahriHôpital Aziza Othmana Tunis, Tunis, Tunisia.
Roua HsasnaHôpital Aziza Othmana Tunis, Tunis, Tunisia.
Yosr Ben AbdennebiHôpital Aziza Othmana Tunis, Tunis, Tunisia.
Lamia AissaouiHôpital Aziza Othmana Tunis, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In children, acute promyelocytic leukemia is a distinct and underreported entity. The objective of our study is to report the therapeutic outcomes of APL in the pediatric population. Methods: This was a descriptive, retrospective, single-center study including 30 patients diagnosed with APL over an 18-year period. Patients were treated in the Hematology Department of Aziza Othmana Hospital in Tunis. Results: The median age at diagnosis was 11 years, with a sex ratio of 0.87. Half of the patients were classified as high-risk. Post-induction cytologic remission was achieved in 86.6 % of patients. There were five cases of relapse, 60 % of which were early relapses. The 5-year overall survival rate was 70.6 %.The 5-year event-free survival rate was 72 %. The 5-year relapse-free survival rate was 80 %. Conclusion: Although our results were satisfactory, they revealed a poor prognosis for relapsed patients. A larger study focusing on relapse characteristics is needed.

Indexed as

AcuteATRAChildrenLeukemiaPromyelocytic

Identifiers

PMID41994845
PMCPMC13080681

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