ArticleCureus2026
Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis With Polyangiitis in a Pediatric Patient.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare pediatric vasculitis that can be difficult to diagnose, especially when antineutrophil cytoplasmic antibody (ANCA) is negative. We describe the case of a 10-year-old girl with severe asthma, recurrent leukocytoclastic vasculitis, peripheral eosinophilia, and pulmonary nodules. Infectious and immunologic workup was unremarkable, and skin biopsy confirmed eosinophilic vasculitis. She was diagnosed with ANCA-negative EGPA based on the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology criteria and started on high-dose corticosteroids with plans for mepolizumab maintenance. This case highlights the diagnostic challenges in pediatric EGPA, the masking effects of biologic therapy, and the importance of multidisciplinary evaluation for early recognition and optimal management.
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