Evidence map›Paper›PMID 41994829›Full record

ArticleCureus2026

An Uncertain Cardiac Mass: A Case of Whipple's Disease.

Jessica Fidalgo, Carina Santos, Sonia Coelho, Catarina Quinaz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica FidalgoInternal Medicine, Unidade Local de Saúde (ULS) Guarda, Guarda, PRT.
Carina SantosInternal Medicine, Unidade Local de Saúde (ULS) Guarda, Guarda, PRT.
Sonia CoelhoInternal Medicine, Unidade Local de Saúde (ULS) Guarda, Guarda, PRT.
Catarina QuinazInfectious Disease, Unidade Local de Saúde (ULS) Guarda, Guarda, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whipple's disease is a rare multisystem infectious disorder with a heterogeneous clinical presentation that frequently leads to delayed diagnosis. Relapses may occur even years after apparent remission. We report a 54-year-old man with a previous diagnosis of Whipple's disease who presented with fatigue, weight loss, anemia, and recurrent gastrointestinal symptoms. Echocardiography showed a persistent aortic valve mass with progressive regurgitation in the setting of repeatedly negative blood cultures and minimal systemic inflammatory response. Upper gastrointestinal endoscopy with duodenal biopsies revealed periodic acid-Schiff-positive macrophages, and real-time polymerase chain reaction confirmed

Indexed as

multidisciplinary decision-makingsubacute endocarditissurgical valve replacementvalvular regurgitationwhipple's disease

Identifiers

PMID41994829
PMCPMC13082768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.