Evidence map›Paper›PMID 41994649›Full record

ArticleFrontiers in oncology2026

Differentiation of bilateral BI-RADS 4 breast lesions with one benign and one malignant finding using dual-layer detector spectral CT: a case report.

Ying Chen, Qi Wang, Qian Xu, Xiangyao Gong, Jing Wen, Lili Zhou, Yu Du

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ying ChenDepartment of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Qi WangDepartment of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Qian XuDepartment of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Xiangyao GongDepartment of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Jing WenPhilips (China) Investment Co., Ltd., Beijing Branch, Beijing, China.
Lili ZhouPhilips (China) Investment Co., Ltd., Beijing Branch, Beijing, China.
Yu DuDepartment of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The differentiation between benign and malignant BI-RADS 4 breast lesions remains a significant clinical challenge, particularly when multi-modal imaging assessments yield inconsistent results, often leading to diagnostic dilemmas. Dual-layer detector spectral computed tomography (CT) (DLCT), as an imaging modality, provides multi-parametric quantitative information and holds promise as a tool for lesion differentiation. Here, we present a case of bilateral breast lesions. Although ultrasound assessed both as BI-RADS 4, subsequent mammography, magnetic resonance imaging (MRI), and CT yielded discordant findings for the right lesion. Retrospective analysis of the preoperative DLCT data clearly revealed the intrinsic differences between the bilateral lesions. This accurately predicted malignancy on the left side and benignity on the right side, which was in complete concordance with the final surgical pathological findings.

Indexed as

benign-malignant differentiationBI-RADS 4breast lesionsquantitative imagingspectral CT

Identifiers

PMID41994649
PMCPMC13078999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.