Evidence map›Paper›PMID 41994594›Full record

ArticleCase reports in dentistry2026

Two-Year Outcomes of Regenerative Therapy in an Immature Maxillary Molar With Periapical Abscess: A Case Report.

Luiz Felipe Rodrigues Siqueira, Thais Caetano de Souza-Guedes, Laura Ferreira Araujo, Paulo Ricardo de Sousa Pereira, Crisnicaw Veríssimo, Patrícia Correia de Siqueira, Juliano Gonçalves Miguel, Orlando Aguirre Guedes, Gustavo Silva Chaves

Abstract read
In one paragraph

Article in Case reports in dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luiz Felipe Rodrigues SiqueiraDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0000-0001-6730-2976
Thais Caetano de Souza-GuedesDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0009-0007-9490-9918
Laura Ferreira AraujoDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0009-0009-4004-1548
Paulo Ricardo de Sousa PereiraDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0009-0009-1354-5070
Crisnicaw VeríssimoDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0000-0002-8146-9606
Patrícia Correia de SiqueiraDepartment of Stomatology, School of Dentistry, Federal University of Goiás, Goiânia, Goiás, Brazil, ufg.br.ORCID https://orcid.org/0000-0003-4909-8611
Juliano Gonçalves MiguelDepartment of Oral Biology, School of Dentistry, Alfredo Nasser University Center, Goiânia, Goiás, Brazil.ORCID https://orcid.org/0009-0004-2493-2483
Orlando Aguirre GuedesDepartment of Endodontics, School of Dentistry, Pontifical Catholic University of Goiás, Goiânia, Goiás, Brazil, pucgoias.edu.br.ORCID https://orcid.org/0000-0003-1664-329X
Gustavo Silva ChavesDepartment of Endodontics, School of Dentistry, Pontifical Catholic University of Goiás, Goiânia, Goiás, Brazil, pucgoias.edu.br.ORCID https://orcid.org/0000-0003-1721-1595

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trauma or caries in teeth with incomplete root formation can lead to pulp necrosis. Endodontic treatment in such cases requires specific clinical protocols that differ from conventional approaches due to the anatomical and developmental characteristics of immature teeth. This case report describes the clinical management of a maxillary second molar (tooth #17) with incomplete root development and a periapical abscess, treated through pulp revascularization. A 13-year-old male patient presented with spontaneous, throbbing pain in the upper right facial region, accompanied by infraorbital swelling. Intraoral examination revealed extensive loss of tooth structure in tooth #17 and the presence of a palatal abscess. Cold pulp testing was negative, while percussion testing was positive, supporting the diagnosis of periapical abscess. Due to the extensive tooth structure, a crown lengthening procedure was performed. Endodontic access was achieved under rubber dam isolation, and three root canals were identified and carefully emptied. Irrigation was performed with 2.5% sodium hypochlorite 4 mm short from the working length, followed by 3 min of EDTA application. Ultracal was used as intracanal medicament for 30 days. At the second appointment, clot induction was achieved with a #20 file, and the cervical third was sealed with Biodentine, followed by composite resin restoration. After a 2-year clinical, radiographic, and tomographic follow-up, the tooth remained asymptomatic, with radiographic evidence of continued root maturation and apical closure, suggesting a favorable outcome of the regenerative protocol.

Indexed as

dental pulp necrosismaxillary molarperiapical abscessregenerative endodontics

Identifiers

PMID41994594
PMCPMC13082468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.