SynthesisFrontiers in public health2026
Occupational exposure to inhalational anesthetics and the risk of spontaneous abortion: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- When behavior outweighs infrastructure: disinfectant and latex exposure and preventive practice among operating room nurses in China.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Healthcare professionals, particularly anesthesiologists, nurses, and dental staff, are routinely exposed to inhalational anesthetic agents such as nitrous oxide and halogenated gases. Although scavenging and ventilation systems have reduced ambient levels, concerns remain regarding reproductive risks associated with chronic exposure. Previous studies have yielded inconsistent results. A systematic review and meta-analysis of published observational studies was conducted to clarify the relationship, assessing reproductive outcomes among healthcare workers who were exposed. Objective: This systematic review and meta-analysis aimed to clarify the association between occupational exposure to anesthetic gases and the risk of spontaneous abortion among healthcare workers. Methods: A systematic search was performed in PubMed, Scopus, and Web of Science up from inception until the end of July 2025. Observational studies assessing spontaneous abortion among female healthcare workers exposed to inhalational anesthetics were included. Two reviewers independently screened and extracted data and assessed study quality using the Newcastle-Ottawa Scale (NOS). Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random-effects model. Heterogeneity was evaluated using the I Results: Seventeen studies were included. The pooled analysis showed 1.29-fold higher odds of spontaneous abortion among exposed workers compared with unexposed controls (OR = 1.29; 95% CI: 0.96-1.75; I Conclusion: Occupational exposure to anesthetic gases may increase the risk of spontaneous abortion, particularly in those who are at high exposure, emphasizing the need for stringent exposure control and improved workplace safety standards.
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