ArticleJGH open : an open access journal of gastroenterology and hepatology2026
Dietary Vitamin B6 Intake and Gastroesophageal Reflux Disease: A Case-Control Study.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder influenced by various dietary factors. This study aimed to evaluate the association between dietary intake of vitamin B6 and the risk of GERD. Methods: This case-control study included 150 women with GERD and 300 controls in Tehran, Iran. Dietary intake of vitamin B6 was assessed using a validated food frequency questionnaire (FFQ) and analyzed with Nutritionist IV software. Logistic regression models were applied to determine the association between GERD risk and dietary intake of vitamin B6, adjusting for age, education, marital status, occupation, physical activity, BMI, and calorie intake. Results: Compared with participants in the lowest tertile of vitamin B6 intake, those in the highest tertile had significantly higher odds of GERD in age-adjusted models (OR = 1.98, 95% CI: 1.12-3.51) and this association remained significant after further adjustment for sociodemographic factors, physical activity, BMI (OR = 2.05, 95% CI: 1.10-3.83), and total energy intake (OR = 2.02, 95% CI: 1.06-3.81). No significant association was observed for the middle tertile. Conclusion: The findings of this case-control study indicate a positive association between higher dietary vitamin B6 intake and the risk of GERD. Further prospective research would be helpful to confirm these observations and to shed light on possible biological mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.