ArticleFrontiers in medicine2026
Lung allograft injury improves after gastroesophageal reflux surgery by donor-derived cell-free DNA kinetics.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Gastroesophageal reflux disease (GERD) and bile acid micro-aspiration are risk factors for the development of chronic lung allograft dysfunction (CLAD) after lung transplantation (LT). Donor-derived cell-free DNA (dd-cfDNA) is a clinically validated plasma biomarker for acute rejection but also detects other types of allograft injury and can potentially be used to detect GERD and micro-aspiration. Here, we report a five-case single-center series of LT patients with confirmed GERD and micro-aspiration, treated by Toupet fundoplication and adjunctive laparoscopic procedures. dd-cfDNA fraction measured pre
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