Evidence map›Paper›PMID 41994444›Full record

ArticleFrontiers in medicine2026

Propensity-matched study of liposomal doxorubicin vs. doxorubicin in first-line DLBCL treatment: efficacy and safety.

Lin Zeng, Chao Tang, Hao Cheng, Xianwei Peng, Xuanzhang Li, Xiaohong Tan, Jie Sun, Changxian Chen, Hong Cen, Chengcheng Liao

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lin Zeng *Department of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Chao Tang *Department of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Hao Cheng *Department of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Xianwei PengDepartment of Hematology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xuanzhang LiDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Xiaohong TanDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Jie SunDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Changxian ChenDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Hong CenDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Chengcheng LiaoDepartment of Hematology/Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Given the increasing use of pegylated liposomal doxorubicin (PLD) in diffuse large B-cell lymphoma (DLBCL) treatment due to its advantages in reducing adverse reactions, and the uncertainty surrounding its effective dose and corresponding efficacy in DLBCL, this study aims to compare it with the standard dose of conventional doxorubicin (DOX) in first-line DLBCL treatment. Methods: A retrospective propensity score-matched analysis of 512 DLBCL patients (2018-2023) compared PLD {stratified: low-dose [21.5 (5-25.5) mg/m Results: Overall PLD and DOX showed comparable 2-year PFS (74.3% vs. 69.6%, Conclusion: High-dose PLD [29.5 (25.5-40) mg/m

Indexed as

diffuse large B-cell lymphomadoxorubicinoverall survivalpegylated liposomal doxorubicinprogression-free survival

Identifiers

PMID41994444
PMCPMC13079127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.