ArticleFrontiers in medicine2026
Diagnostic utility of procalcitonin in determining Gram-negative and Gram-positive bacterial bloodstream infections: a single-centre study from South India.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Bloodstream infections (BSIs) are significant contributors to global morbidity and mortality, with sepsis accounting for 11 million deaths annually. Accurate and rapid diagnosis is essential for effective management. Methods: This retrospective analysis was conducted on 275 positively flagged blood culture bottles collected over one year. Samples were processed using automated blood culture systems, followed by pathogen identification and antimicrobial susceptibility testing (AST) via the Vitek-2 Compact system (bioMérieux, France). PCT (Procalcitonin) levels were measured using MINIVIDAS (bioMérieux, France) and correlated with pathogens to evaluate diagnostic accuracy. Results: Among 251 isolates, Gram-negative bacteria predominated (77.68%), with Enterobacterials like Conclusion: PCT levels were elevated in both Gram-negative and Gram-positive BSIs, with marginally higher values in Gram-negative infections. Significant elevations in Gram-positive infections, particularly with
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