ArticlePakistan journal of medical sciences2026
Efficacy and safety of different intensities of anticoagulation with warfarin in elderly patients with non-valvular atrial fibrillation.
Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the efficacy and safety of different intensities of warfarin anticoagulant therapy in elderly patients with non-valvular atrial fibrillation (NVAF). Methodology: This retrospective study was conducted at Chun'an First People's Hospital. Clinical records of 108 elderly patients with NVAF who received warfarin anticoagulant therapy from January 2022 to August 2023 were included. Among them, 54 patients were assigned to the low-intensity anticoagulation group (international normalized ratio [INR] 1.6-2.0), and 54 patients comprised the standard-intensity anticoagulation group (INR 2.1-3.0). All patients were followed up for 24 months. The creatinine clearance (Ccr) before treatment and at 3, 6, 12, and 24 months after treatment was assessed. Incidents of thromboembolism and bleeding in the two groups during the follow-up period were compared. Results: There were no statistically significant differences in the Ccr levels between the two groups before treatment and at each time point after treatment ( Conclusions: The results of this study indicate that low-intensity warfarin anticoagulation has similar renal function outcomes (as assessed by creatinine clearance) to standard-intensity anticoagulation, with no increase in the risk of thromboembolism. However, low-intensity anticoagulation is associated with a lower risk of bleeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.