ArticlePakistan journal of medical sciences2026
Quality of Life in relation to Vitamin-D levels in asymptomatic young health care professionals in a tertiary care hospital: Quality of Life and Vitamin-D (QoLD) study.
Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: We have assessed the Vitamin-D status and its association with health-related quality of life in healthy young health care professionals in a tertiary care hospital in Pakistan. Methodology: This cross-sectional study was performed in the Department of Diabetes, Endocrinology and Metabolic Diseases, Hayatabad Medical Complex, Peshawar, Pakistan. Three hundred and nineteen healthy young health care professionals (HCPs) aged 20-40 years of age were enrolled in July 2023 using non-probability convenient sampling method. Vitamin-D status was categorized as deficient (<20 ng/ml), insufficient (21-29 ng/ml), or sufficient (≥30 ng/ml) per Endocrine Society guidelines. The Medical Outcomes Study 36-Item Short Form Health Survey measured health related quality of life (HRQoL). ANOVA compared continuous variables, while Chi-square tested categorical variables. A p value < 0.05 indicated statistical significance in the two-sided analysis. Results: From July 1st to July 31st, 2023, 319 individuals were recruited, with a mean age of 28.2 ± 4.96 years, with 230 (72.1%) males and 89 (27.9%) females. The mean serum 25-hydroxyVitamin-D concentration was 24.9 ± 9.55 ng/ml with 82.1% being either deficient or insufficient. The mean physical component score (PCS), mental component score (MCS) and total short form-36 (SF-36) score were 81.2 ± 11.4, 77.9 ± 12.9 and 79.6 ± 11.1 respectively. Vitamin-D did not affect total SF-36 score (p=0.09). Only role limitation due to emotional issues (p=0.04), energy/fatigue (p=0.04), and emotional wellness (p=0.03) showed significant differences, with lower scores in the deficient group. Conclusion: Most healthy young HCPs were Vitamin-D insufficient, whilst 95% had a mean SF-36 score >50. However, there was no relationship between Vitamin-D status and the quality of life.
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