Evidence map›Paper›PMID 41994330›Full record

ArticleiScience2026

GSK-3β/β-TrCP regulates Nrf2-mediated oxidative stress response in

Yile Hu, Jinhua An, Han Qiu, Qinglian Wu, Jianqing Li, Gang Yang, Baoqing Hu, Chungen Wen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yile HuCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Jinhua AnCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Han QiuCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Qinglian WuCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Jianqing LiCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Gang YangCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Baoqing HuCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.
Chungen WenCollege of Life Science, Key Laboratory for Aquatic Germplasm Innovation and Utilization of Jiangxi Province, Education Ministry Key Laboratory of Poyang Lake Environment and Resource Utilization, Nanchang University, Nanchang 330031, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear factor erythroid 2-related factor 2 (Nrf2) orchestrates antioxidant and cytoprotective responses. Beyond classical Keap1-dependent redox regulation, Nrf2 activation can occur via the GSK-3β/β-TrCP pathway during Keap1 inhibition. This study investigated this non-canonical pathway in the stress adaptation of the bivalve (

Indexed as

BiochemistryMolecular biology

Identifiers

PMID41994330
PMCPMC13080398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.