Evidence map›Paper›PMID 41994322›Full record

ReviewFrontiers in radiology2026

Artificial intelligence in the diagnosis of thyroid diseases: applications and challenges.

Huayi Zhao, Tingyu Xue, Yan Zhang, Yanchao Lu, Danning Wang, Pei Yin, Lei Jiang, Dan Liu, Yong Wang

Abstract readReview
In one paragraph

Review in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huayi ZhaoDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Tingyu XueDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Yan ZhangDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Yanchao LuDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Danning WangDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Pei YinDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Lei JiangDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Dan LiuDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Yong WangDepartment of Radiology and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid diseases, a prevalent class of endocrine system disorders, require diagnostic accuracy, which is essential for effective patient treatment and management. In recent years, artificial intelligence (AI) technology has made significant advancements in the medical field, providing new opportunities for the early diagnosis and precise treatment of thyroid diseases. This review discusses the latest applications of AI in the diagnosis of thyroid diseases, with a particular focus on the use of machine learning and deep learning (DL) algorithms in image classification, segmentation, and object detection within thyroid ultrasound, computed tomography, magnetic resonance imaging, and single photon emission computed tomography. Through the integration of cross-modal studies, this article reveals the application of AI across various imaging modalities, highlighting its potential value in feature extraction and risk stratification. Furthermore, we conduct an in-depth analysis of key challenges faced by AI applications, such as data heterogeneity (the decline in model performance due to data differences across institutions and equipment) and insufficient interpretability (DL models often function as "black boxes," making it difficult to provide transparent decision-making rationale, which limits clinical trust and adoption). In summary, AI technology demonstrates notable advantages and developmental potential in the automated diagnosis of thyroid diseases; however, its clinical translation still requires addressing the aforementioned challenges. The resultant analysis demonstrates that AI holds promise in improving the diagnosis and treatment of thyroid diseases, offering new pathways for personalized medicine and better patient outcomes. Specifically, AI-driven tools can reduce diagnostic variability and errors in thyroid nodule assessment, enhance treatment precision with risk-stratified recommendations, and support more consistent, individualized clinical decisions.

Indexed as

AIclassificationdeep learningdetectionsegmentationthyroidthyroid imaging modalities

Identifiers

PMID41994322
PMCPMC13079602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.