Evidence map›Paper›PMID 41994252›Full record

ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

Stromal graft rejection after deep anterior lamellar keratoplasty at a tertiary care center.

Khalid S Almousa, Majed S Alkharashi

Abstract read
In one paragraph

Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Khalid S AlmousaDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Majed S AlkharashiDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the characteristics and outcomes of stromal rejection after deep anterior lamellar keratoplasty (DALK) at a tertiary care center in Saudi Arabia.

methodsThe clinical records of 42 patients who underwent DALK between January 2019 and December 2023 were reviewed to identify patients who had experienced stromal rejection. Those patients were analyzed in terms of biodata, indications for surgery, graft size, subjective and objective clinical findings, treatment courses, and follow-ups.

resultsOf the 42 cases of DALK conducted during the study in our center, 3 (7.1%) experienced graft rejection between postoperative months 8 and 18. The mean age of patients with rejection at presentation was 30.6 years, compared to 33.5 years for those without rejection. The mean follow-up durations were 16.6 months for patients with rejection and 25.7 months for patients without rejection. All patients started intensive topical prednisolone acetate 1% (half hourly to hourly) on first presentation, and one had a pulse of intravenous methylprednisolone. A complete recovery was observed in all patients after 1-2 weeks.

conclusionWhile DALK offers significant advantages over full-thickness corneal grafting, graft rejection remains a potential complication. Early presentation and timely treatment of rejection after DALK carry a good prognosis and can prevent graft failure.

Indexed as

Graft rejectionlamellar keratoplastystromal edemasubepithelial infiltrates

Identifiers

PMID41994252
PMCPMC13082552

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