ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
Ocular microvascular alterations in epileptic patients.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThe brain and eye are linked by the same nerves and arteries, presenting a hemodynamic continuity. Alterations in ocular perfusion may have an impact on the visual function or the neurodegenerative process. We aimed to assess whether there is a relationship between epilepsy and ocular microvasculature in the adult population by optical coherence tomography angiography (OCTA).
methodsThis observational, cross-sectional study included 22 epilepsy patients (epilepsy group), and 21 healthy controls (control group). OCTA analysis of the vessel density (VD) of the retinal superficial capillary plexus, deep capillary plexus, foveal retinal thickness (FRT), foveal avascular zone (FAZ) areas, and the radial peripapillary capillary, and retinal nerve fiber layer (RNFL) thickness were evaluated.
resultsAge, gender, central corneal thicknesses, and mean intraocular pressure levels were similar between the groups (
conclusionBesides the neurological basis of epilepsy, vascular dysfunction seems to be another risk factor in the pathophysiology of epilepsy. OCTA may be suggested as a potentially useful biomarker for ocular microvascular alterations in epileptic patients.
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