Evidence map›Paper›PMID 41994235›Full record

ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

The efficacy and safety of biweekly valganciclovir 450 mg for prophylaxis of recurrent cytomegalovirus anterior uveitis.

Nancy Hazem, Hind Amin, Samir Shoughy

Abstract readCase Reports
In one paragraph

Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nancy HazemDepartment of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Hind AminDepartment of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Samir ShoughyDoctor Samir Eye Clinic, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral anterior uveitis (AU) can be caused by a multitude of viruses, including cytomegalovirus (CMV). It can be a potentially vision-threatening condition. Thus, it requires prompt diagnosis and treatment as well as long-term prophylaxis to prevent the dire effects of recurrences. This case involved a 45-year-old Egyptian woman with a long history of unilateral recurrent AU that was polymerase chain reaction proven to be due to CMV. She was treated with oral valganciclovir and then placed on maintenance therapy. In this case, we shed the light on the possibility of reducing the prophylactic dose to a 450 mg biweekly dose of oral valganciclovir. Considering a lower dose of oral valganciclovir may help practitioners avoid the side effects of oral valganciclovir as well as reduce the overall financial burden in long-term prophylaxis.

Indexed as

Anterior uveitiscytomegalovirusprophylaxisvalganciclovirviral uveitis

Identifiers

PMID41994235
PMCPMC13082554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.