ArticleResearch square2026
Laminar-specific control of response gain and orientation-tuning by parvalbumin-expressing inhibitory interneurons in primate visual cortex.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Understanding the role of different inhibitory interneuron subtypes in cortical computations is essential for explaining sensory processing in the neocortex. Orientation tuning in primate primary visual cortex (V1) provides a canonical model for studying how cortical sensory circuits and inhibitory interneurons compute relevant stimulus features. The selective feedforward convergence of non-orientation-selective thalamic afferents establishes initial orientation tuning in the granular V1 input layer. As signals propagate through the cortical microcircuit, orientation tuning sharpens in extra-granular layers, yet the underlying mechanisms and the contribution of specific inhibitory neuron subtypes remain unresolved. To study the role of the largest cortical inhibitory neuron subclass, parvalbumin-expressing (
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