ArticleResearch square2026
PvDBP gene amplification is associated with functional immune evasion by Plasmodium vivax in vivo.
Léa Baldor, Dynang Seng, Sokleap Heng, Nimol Khim, Sreyneat Hor, Sopheany Thin, Nichole Salinas, Niraj Tolia, Chetan Chitnis, Ivo Mueller and 7 more
Abstract readPreprint
In one paragraphArticle in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Léa BaldorInstitut Pasteur du Cambodge.
Dynang SengInstitut Pasteur du Cambodge.
Sokleap HengInstitut Pasteur du Cambodge.
Nimol KhimInstitut Pasteur du Cambodge.
Sreyneat HorInstitut Pasteur du Cambodge.
Sopheany ThinInstitut Pasteur du Cambodge.
Nichole SalinasNational Institute of Allergy and Infectious Disease.
Chetan ChitnisInstitut Pasteur.
Christopher KingCenter for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio, USA 44106.ORCID 0000-0003-3873-7860 Eugenia LoDrexel University.
Claude FlamandInstitut Pasteur du Cambodge.
Lionel Feufack-DonfackInstitut Pasteur du Cambodge.
Funding
Understanding, tracking and eliminating malaria transmission in the Asia - Pacific RegionU19AI129392 · NIAID · WALTER AND ELIZA HALL INST MEDICAL RES · PI Ivo J Mueller, Leanne Robinson · 2017 to 2026
$7.1MDefining targets of protective immunity to vivax malaria using human monoclonal antibodiesR01AI143694 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI KING, CHRISTOPHER L · 2020 to 2024
$3.6MExtent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplificationR01AI173171 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Eugenia Lo, Jean POPOVICI · 2023 to 2026
$2.4MComprehensive characterization of the genetic factors and the host immune response associated to protection from clinical Plasmodium vivax malariaR01AI175134 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI TINEKE CANTAERT, Jean POPOVICI · 2023 to 2026
$2.3MLeveraging access to parasite natural diversity to identify Plasmodium vivax culture-adaptable strain.R61AI187100 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Jean POPOVICI · 2025 to 2026
$533kBLRD VA I01 BX001350NIAID NIH HHS R01 AI143694NIAID NIH HHS R01 AI173171NIAID NIH HHS R01 AI175134NIAID NIH HHS R61 AI187100NIAID NIH HHS U19 AI129392
6 · The paper itselfAbstract
The key ligand involved in
Identifiers
PMID41994132
PMCPMC13082139
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