Evidence map›Paper›PMID 41993952›Full record

ArticleCase reports in urology2026

Immunotherapy-Related Cystitis Induced by Nivolumab for Advanced Gastric Cancer: A Case Report.

Kentaro Arinami, Kozue Ito, Go Hasegawa, Yurie Takizawa, Yohei Ikeda, Takeshi Suda, Noboru Hara, Tsutomu Nishiyama

Abstract read
In one paragraph

Article in Case reports in urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kentaro ArinamiDepartment of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Kozue ItoDepartment of Pathology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Go HasegawaDepartment of Pathology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Yurie TakizawaDepartment of Diagnostic Radiology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Yohei IkedaDepartment of Diagnostic Radiology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Takeshi SudaDepartment of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Noboru HaraDepartment of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.
Tsutomu NishiyamaDepartment of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Niigata, Japan, niigata-u.ac.jp.ORCID https://orcid.org/0000-0002-5684-8364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old man received treatment for advanced gastric cancer involving capecitabine, oxaliplatin, and nivolumab therapy. Following four courses of this treatment, he developed severe urethralgia and hematopyuria. Urine bacterial culture was negative. Cystoscopy revealed readily bleeding and edematous, reddish mucosa. Computed tomography identified edematous changes in the wall of the bladder, but no lesions were noted in the upper urinary tract. The bladder wall was biopsied, and pathological findings indicated erosion and hemorrhage of the bladder mucosa, accompanied by lymphocytic infiltration. Based on the overall clinical presentation, immunotherapy-associated cystitis induced by nivolumab treatment for advanced gastric cancer was suspected. He began taking prednisolone at a dosage of 25 mg per day, which was gradually tapered over time, and the urinary symptoms markedly improved.

Indexed as

advanced gastric cancercorticosteroid treatmentimmunotherapy-related cystitisnivolumab

Identifiers

PMID41993952
PMCPMC13080257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.