Severe polyarterial involvement in a 16-year-old with homozygous familial hypercholesterolaemia: a case report.

Malak Benabdellah, Mohammed Bachir Mesfioui, Hajar El Ouartassi, Badre El Boussaadani, Zainab Raissuni

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Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Malak BenabdellahCardiology Department, Mohammed VI University Hospital, Tangier 90000, Morocco.ORCID https://orcid.org/0009-0001-2968-7358

Mohammed Bachir MesfiouiCardiology Department, Mohammed VI University Hospital, Tangier 90000, Morocco.

Hajar El OuartassiCardiology Department, Mohammed VI University Hospital, Tangier 90000, Morocco.

Badre El BoussaadaniCardiology Department, Mohammed VI University Hospital, Tangier 90000, Morocco.ORCID https://orcid.org/0000-0002-7931-1615

Zainab RaissuniCardiology Department, Mohammed VI University Hospital, Tangier 90000, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder characterized by an elevated plasma concentration of low-density lipoprotein cholesterol (LDL-C) starting at birth and a significantly increased risk of premature atherosclerotic cardiovascular disease. Case summary: We report the case of a 16-year-old female patient, with no known consanguinity, presented to our cardiology department for anginal chest pain on exertion associated with headaches. She presented with characteristic morphological features of FH. Her lipid profile revealed extremely high LDL-C levels (706 mg/dL) and such extensive arterial and cutaneous involvement. Discussion: This case underscores the importance of recognizing xanthomas and their association with an increased risk of coronary atherosclerosis.

Indexed as

AtherosclerosisCase reportFamilial hypercholesterolaemiaLipid-lowering therapyLow-density-lipoprotein

Identifiers

PMID41993942

DOI10.1093/ehjcr/ytag227

PMCPMC13082219

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