Evidence map›Paper›PMID 41993894›Full record

ArticleFrontiers in pediatrics2026

Association between vaccination status and neurodevelopmental outcomes in children with cerebral palsy.

Hong Zhao, Mingbo Hu, Fei Xie, Chunyu Zhang, Linli Zhang, Chao Bai, Junjie Wu, Baofeng Yan, Aikebaier Halike, Jingxuan Xu and 1 more

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hong Zhao *Cerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Mingbo Hu *Cerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Fei Xie *Cerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Chunyu ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Henan University of Chinese Medicine, Weihui City, China.
Linli ZhangDepartment of Neurology, The First Affiliated Hospital of Henan University of Chinese Medicine, Weihui City, China.
Chao BaiCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Junjie WuCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Baofeng YanCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Aikebaier HalikeCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Jingxuan XuCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Xinping LuanCerebral Palsy Center in Neurosurgery, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The safety of vaccines and their impact on functional outcomes in children with cerebral palsy remain significant concerns for both parents and healthcare providers. These concerns have limited the full implementation of routine immunization schedules in this specific population. Objective: This study aimed to investigate the association between vaccination status and the development of motor and communication functions in children with cerebral palsy. The findings are intended to inform the development of targeted vaccination strategies. Methods: We conducted a bidirectional cohort study involving 484 children diagnosed with cerebral palsy at the Second Affiliated Hospital of Xinjiang Medical University between January 2018 and December 2024. Participants were divided into a retrospective cohort (diagnosed 2018-2020, Results: Children in the vaccinated group demonstrated significantly better motor function, reflected by lower GMFCS levels ( Conclusion: For children with cerebral palsy, routine vaccination is not only safe but may also exert a positive regulatory effect on neurological development. We recommend reinforcing routine immunization in this population and optimizing vaccination strategies through ongoing dynamic follow-up.

Indexed as

bidirectional cohort studycerebral palsycommunication functionimmunization schedulemotor functionvaccination

Identifiers

PMID41993894
PMCPMC13079342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.