Evidence map›Paper›PMID 41993880›Full record

ArticleComputational and structural biotechnology journal2026

MedDiscover: A Domain-Specific Retrieval-Augmented Generation Framework for Evidence-Grounded Knowledge Extraction in Metabolomics.

Vatsal Pravinbhai Patel, Elena Jolkver, Anne Schwerk

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vatsal Pravinbhai PatelIU Internationale Hochschule GmbH, 99084 Erfurt, Germany.ORCID https://orcid.org/0000-0001-5751-4430
Elena JolkverIU Internationale Hochschule GmbH, 99084 Erfurt, Germany.ORCID https://orcid.org/0000-0003-4711-6708
Anne SchwerkIU Internationale Hochschule GmbH, 99084 Erfurt, Germany.ORCID https://orcid.org/0000-0002-5014-5289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrieval-augmented generation (RAG) can improve biomedical question answering, but claims about domain-specific retrievers require transparent, reproducible evaluation. We present MedDiscover, an open-source RAG implementation and benchmark instantiated for metabolomics and metabolic-disorder literature, with a 2-tier dataset design: a Gold set of 10 papers and 30 expert-curated question-answer (QA) pairs with traceable references, and a Silver set of 100 papers curated using International Statistical Classification of Diseases and Related Health Problems 10th Revision metabolic disorder codes E70 to E88 with ~600 synthetic QA pairs and retrievability metadata (Ada

Identifiers

PMID41993880
PMCPMC13082540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.