ReviewFrontiers in cardiovascular medicine2026
Effect of sarcopenia on risk of atrial fibrillation: a systematic review and meta-analysis of observational studies.
Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comments on "Longitudinal Association Between Possible Sarcopenia and Stroke Under the AWGS 2025 Criteria: A Nationwide Prospective Cohort Study With a 9-Year Follow-Up".Geriatrics & gerontology international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The association between sarcopenia and risk of atrial fibrillation (AF) remains uncertain. In this study, we aimed to quantify the association between sarcopenia and the risk of AF through a meta-analysis of observational cohort studies. Methods: PubMed, Web of Science, EMBASE, and major scientific conference sessions were searched without language restrictions from inception to 15 August 2025. Bibliographies of relevant articles were also manually searched. Observational studies that evaluated the association between sole or combined components of sarcopenia criteria and risk of AF were included. Results: Ten studies involving 7,358,442 participants were included in the meta-analysis. Sarcopenia was significantly associated with an increased risk of AF onset [pooled hazard ratio (HR) = 1.44, 95% CI: 1.22-1.68], with high heterogeneity among studies ( Conclusions: The results of our study demonstrated that sarcopenia is associated with a 44% increased risk of AF onset compared with non-sarcopenia individuals. The association was independent of sex, age, geographic location, duration of follow-up, BMI status, and regular physical activity. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251020653 identifier, CRD420251020653.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.