Evidence map›Paper›PMID 41993854›Full record

ArticleFrontiers in cardiovascular medicine2026

Effect of obstructive sleep apnea-hypopnea syndrome on myocardial mechanics in obese patients.

Xiaoyan Kang, Jiping Xue, Min Zhao, Yanxia Zhang, Junwang Miao, Shuai Li, Chunsong Kang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaoyan Kang *Department of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Jiping Xue *Department of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Min ZhaoDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Yanxia ZhangDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Junwang MiaoDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Shuai LiDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.
Chunsong KangDepartment of Ultrasonography, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Obesity and obstructive sleep apnea-hypopnea syndrome (OSAHS) often coexist. Chronic intermittent hypoxia in OSAHS can compound cardiac remodeling, but the comprehensive impact of OSAHS severity on obese patients remains unclear. Methods: A total of 83 obese patients were included in this study and divided into the obesity-only group (27 cases) and the obesity-OSAHS group (56 cases) based on the presence of OSAHS. An additional 30 healthy individuals served as the control group. According to the apnea-hypopnea index (AHI), the obesity-OSAHS group was further classified into a mild group (30 cases), moderate group (16 cases), and severe group (10 cases). Echocardiographic and strain parameters were compared across these groups, and factors influencing global longitudinal strain (GLS) were analyzed. Results: Left ventricular GLS progressively declined across the control group (-21.28%), obesity-only group (-18.85%), and obesity-OSAHS group (-17.03%) (all P<0.05). Within the OSAHS group, GLS decreased with increasing severity: mild (-18.00%), moderate (-16.69%), and severe (-14.69%) (all Conclusion: Obese patients exhibit impaired myocardial mechanics, which is further aggravated by OSAHS. With increasing OSAHS severity, GLS declines and myocardial dysfunction worsens. AHI and LVMI are independent risk factors for this dysfunction in obese patients with OSAHS.

Indexed as

echocardiographymyocardial mechanicsobesityobstructive sleep apnea–hypopnea syndrometwo-dimensional speckle tracking

Identifiers

PMID41993854
PMCPMC13078984

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