ReviewFrontiers in plant science2026
Multifaceted roles of SCRM/ICE1 in stomatal development, cold stress and beyond.
Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Molecular mechanisms underlying the maintenance of terminal differentiation in Arabidopsis guard cells.Frontiers in plant science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basic helix-loop-helix transcription factor SCREAM (SCRM), also known as INDUCER OF CBF EXPRESSION 1 (ICE1), functions as a regulatory hub that integrates environmental and hormonal signals to mediate diverse aspects of plant development and stress adaptation. Initially characterized for its roles in cold tolerance and stomatal development, recent studies have expanded its functional landscape to include reproductive development, seed dormancy, leaf senescence, and immune modulation. This review synthesizes current knowledge of SCRM/ICE1's multifaceted functions across the plant life cycle, summarizing its molecular regulatory networks in development and stress responses respectively, and highlighting its central role as a regulatory node. By consolidating these dispersed findings, we discuss the balance between developmental programming and stress adaptation mediated by SCRM/ICE1, identify key questions for future research, and explore its potential applications in crop genetic improvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.