Evidence map›Paper›PMID 41993641›Full record

Trial reportFrontiers in neurology

Effect of acupuncture on ischemic stroke patients with hypertension: a randomized clinical trail.

Wei Liu, Boxuan Li, Mengying Rong, Chen Li, Qi Zhao, Lili Zhang, Xiaochan Tan, Qiuxia He, Haipeng Ban, Xianggang Meng and 6 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02967484 (Acupuncture Lowering Blood Pressure for Secondary Prevention of Stroke), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02967484 naunknown statusnot on this map

Acupuncture Lowering Blood Pressure for Secondary Prevention of Stroke: Study Protocol for a Multicenter, Pragmatic,Randomized Controlled, Assessor-blinded Clinical Trial

TypeinterventionalSponsorFirst Teaching Hospital of Tianjin University of Traditional Chinese MedicineRan2016 to 2020Enrolled480ConditionsCerebral InfarctionArmsacupuncture
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wei Liu *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Boxuan Li *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Mengying Rong *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Chen LiFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Qi ZhaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Lili ZhangFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Xiaochan TanAcupuncture Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, China.
Qiuxia HeTianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Haipeng BanFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Xianggang MengFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Wenlong GuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Xinxin GaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Fen MaTianjin Hongshunli Street Community Health Service Center, Tianjin, China.
Mi OuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Xuemin ShiFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.
Yuzheng DuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited evidence suggests that acupuncture has a short-term antihypertensive effect. The efficacy and safety of acupuncture as an adjunctive treatment for ischemic stroke patients with hypertension were uncertain. Objective: To investigate the efficacy and safety of acupuncture as adjunctive therapy in reducing stroke recurrence and improving blood pressure for stroke patients with hypertension. Design: Multicenter randomized, controlled trial. Methods: 18 centers from September 2015 to January 2020. 480 stroke participants with hypertension were randomized into adjunctive acupuncture group and basic treatment group to complete a 12-week treatment. The primary outcome was the one-year recurrence of stroke and the secondary outcome in 48-week follow-up included blood pressure, the Traditional Chinese Medicine syndrome score, the Short Form 36-item Health Survey, the National Institute of Health Stroke Scale, the Barthel Index scale, the ultrasound doppler, and serum tests. Results: There were no statistical differences between groups in primary outcome ( Conclusion: Adjunctive acupuncture therapy can improve stroke patients' circadian rhythm, carotid blood flow, and quality of life, but may not have a superior effect on reducing one-year stroke recurrence. Clinical trial registration: ClinicalTrials.gov, identifier NCT02967484.

Indexed as

acupunctureblood pressurehypertensionrandomized clinical trialstroke

Identifiers

PMID41993641
PMCPMC13079042

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.