Evidence map›Paper›PMID 41993519›Full record

ArticlebioRxiv : the preprint server for biology2026

Telomeric amplicons of

Bonita J Brewer, Rebecca Martin, Elizabeth Ramage, Celia Payen, Sara C Di Rienzi, Yang Zhao, Kelsey Zane, Jocelyn Verhey, Miranda Zalusky, Danny E Miller and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Bonita J BrewerDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0001-8782-0471
Rebecca MartinDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0002-0498-3329
Elizabeth RamageDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0009-0008-6199-9862
Celia PayenDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0003-3717-5579
Sara C Di RienziDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0002-6188-663X
Yang ZhaoDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0009-0004-3522-1804
Kelsey ZaneDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0009-0002-0645-3564
Jocelyn VerheyDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0009-0004-8777-3870
Miranda ZaluskyDivision of Genetic Medicine, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington.ORCID 0000-0002-4721-7499
Danny E MillerDivision of Genetic Medicine, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington.ORCID 0000-0001-6096-8601
Giang T OngDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0002-3946-1627
Jamie L McKeeDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0009-0007-6088-5997
Gina M AlvinoDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0002-1305-2155
Maitreya J DunhamDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0001-9944-2666
M K RaghuramanDepartment of Genome Sciences, University of Washington, Seattle, Washington.ORCID 0000-0003-2382-3707

Funding

EUKARYOTIC CHROMOSOME STRUCTURE AND REPLICATIONR01GM018926 · NIGMS · UNIVERSITY OF WASHINGTON · PI BREWER, BONITA J · 1985 to 2016
$6.8M
Choreography of Eukaryotic DNA ReplicationR35GM122497 · NIGMS · UNIVERSITY OF WASHINGTON · PI BONITA J BREWER · 2017 to 2026
$5.7M
Long-read DNA and RNA sequencing to identify disease-causing genetic variation and streamline testingDP5OD033357 · OD · UNIVERSITY OF WASHINGTON · PI MILLER, DANNY ERWIN · 2022 to 2025
$1.9M
Causes and consequences of gene copy number change in adapting yeast populationsR01GM094306 · NIGMS · UNIVERSITY OF WASHINGTON · PI DUNHAM, MAITREYA J · 2011 to 2015
$1.3M
NIGMS NIH HHS R01 GM018926NIGMS NIH HHS R01 GM094306NIGMS NIH HHS R35 GM122497NIH HHS DP5 OD033357
6 · The paper itself

Abstract

Gene amplification is a potent driver of evolution and is thought to contribute to genetic diseases, including cancer. The yeast

Identifiers

PMID41993519
PMCPMC13081905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.