Evidence map›Paper›PMID 41993507›Full record

ArticlebioRxiv : the preprint server for biology2026

End-to-end evaluation of pipelines for metagenome-assembled genomes reveals hidden performance gaps.

Izaak Coleman, Jiong Ma, Gordon Qian, Yusheng Jiang, Aya Brown Kav, Tal Korem

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Izaak ColemanProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-4697-6079
Jiong MaProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.
Gordon QianProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-9603-6275
Yusheng JiangProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.
Aya Brown KavProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-2085-126X
Tal KoremProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0002-0609-0858

Funding

Microbial biomarkers of intestinal MDR colonization after solid organ transplantationR01AI183668 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Tal Korem, Anne-Catrin Uhlemann · 2025 to 2026
$1.7M
NIAID NIH HHS R01 AI183668
6 · The paper itself

Abstract

The generation of Metagenome Assembled Genomes (MAGs) has become a standard and basic step in the analysis of metagenomic data. This multi-step process, which includes assembly, binning, refinement, and quality control, has many alternative approaches, algorithms, and parameters. Determining the ideal approach for a given ecosystem and study, or highlighting algorithmic gaps in need of additional research and development, requires rigorous benchmarking. We present MAG-E (

Identifiers

PMID41993507
PMCPMC13081952

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.