Evidence map›Paper›PMID 41993467›Full record

ArticlebioRxiv : the preprint server for biology2026

METTL14-dependent m

Yu Xi, Jacob Kuempel, Sukwon Choi, Patrick DeSpain, Tianru Zhang, Jiaying Zhu, Abi Osborn, Reed Rivera, Songxiao Zhong, Xiaoyang Wu and 7 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yu XiDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Jacob KuempelDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Sukwon ChoiDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Patrick DeSpainDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Tianru ZhangFormer address: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843.
Jiaying ZhuFormer address: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843.
Abi OsbornDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Reed RiveraDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.
Songxiao ZhongFormer address: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843.
Xiaoyang WuBen May Department of Cancer Research, The University of Chicago, Chicago, IL 60637.
Yong-Xiao WangDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, Ny 12208.
Zhenyu LiDepartment of Pharmaceutical Sciences, Irma Lerma Rangel School of Pharmacy, Texas A&M University, College Station, TX 77845.
A Philip WestThe Jackson Laboratory, Bar Harbor, ME 04609.
Changhao LiFormer address: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843.
Carl W TongDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.ORCID 0000-0003-2479-2498
Xiuren ZhangFormer address: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843.ORCID 0000-0001-8982-2999
Xu PengDepartment of Medical Physiology, Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX 77807.ORCID 0000-0001-9068-102X

Funding

Cardiac Myosin Binding Protein-C in Development and Reversal of Heart FailureR01HL145534 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI TONG, CARL WEI-CHAN · 2019 to 2023
$2.4M
NHLBI NIH HHS R01 HL145534
6 · The paper itself

Abstract

The impact of inflammation on heart failure is increasingly recognized; but how cardiomyocyte restrains innate immune activation remains poorly defined, and nor does the role of N

Identifiers

PMID41993467
PMCPMC13081949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.