Evidence map›Paper›PMID 41993434›Full record

ArticlebioRxiv : the preprint server for biology2026

Epigenomics identifies three sources of DNA methylation in

Matthew Barbisan, Daniel Kim, Sadie Gavriela Drucker, Michelle Lee, Jonathon L Baker

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew BarbisanDepartment of Biomaterial & Biomedical Sciences School of Dentistry Oregon Health & Science University Portland, OR, USA.
Daniel KimDepartment of Biomaterial & Biomedical Sciences School of Dentistry Oregon Health & Science University Portland, OR, USA.
Sadie Gavriela DruckerDepartment of Biomaterial & Biomedical Sciences School of Dentistry Oregon Health & Science University Portland, OR, USA.
Michelle LeeDepartment of Biomaterial & Biomedical Sciences School of Dentistry Oregon Health & Science University Portland, OR, USA.
Jonathon L BakerDepartment of Biomaterial & Biomedical Sciences School of Dentistry Oregon Health & Science University Portland, OR, USA.ORCID 0000-0001-5378-322X

Funding

High Performance Computing and Machine Learning Infrastructure for Oregon Life SciencesS10OD034224 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLROTT, KYLE · 2023 to 2023
$2.0M
Investigating Membrane Alterations as a Mechanism of Acid Tolerance in Cariogenic BacteriaR00DE029228 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BAKER, JONATHON · 2023 to 2025
$747k
Opening Dental and Oral Research Summers (DORS) to Scientific Careers throughout OregonR25DE032536 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KIRSTEN Jeanne LAMPI, Hui Wu · 2023 to 2026
$510k
NIDCR NIH HHS R00 DE029228NIDCR NIH HHS R25 DE032536NIH HHS S10 OD034224
6 · The paper itself

Abstract

DNA methylation is a widespread but incompletely characterized regulatory feature of bacterial genomes. While restriction-modification systems represent well-studied sources of DNA methylation, the full complement of methyltransferases shaping bacterial epigenomes and their physiological consequences remain poorly understood. Here, we used Oxford Nanopore sequencing to comprehensively map DNA methylation in the model oral pathogen

Identifiers

PMID41993434
PMCPMC13081822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.