Evidence map›Paper›PMID 41993406›Full record

ArticlebioRxiv : the preprint server for biology2026

SARM1 is required for macrophage immunophenotype switching that is essential for nerve repair.

Julianna Bennett, Halimah Adesunkanmi, Noah Leever, Grace Bergeron, Josh Small, Cathryn Holladay, Grace Saxman, Rachel E Williamson, Manshi Swain, Gavin Pearson and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julianna BennettDepartment of Biology, Ball State University, Muncie IN 47306, USA.
Halimah AdesunkanmiDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Noah LeeverDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Grace BergeronDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Josh SmallDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Cathryn HolladayDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Grace SaxmanDepartment of Biology, Ball State University, Muncie IN 47306, USA.
Rachel E WilliamsonDepartment of Biology, Ball State University, Muncie IN 47306, USA.
Manshi SwainDepartment of Biological Sciences, University of South Carolina, Columbia SC 29208, USA.
Gavin PearsonDepartment of Biology, Ball State University, Muncie IN 47306, USA.
Manav PatelDepartment of Biology, Ball State University, Muncie IN 47306, USA.
Ashley L KalinskiDepartment of Biology, Ball State University, Muncie IN 47306, USA.ORCID 0000-0001-7611-0810

Funding

Regulation of Neuroinflammation after Peripheral Nerve InjuryR15NS128837 · NINDS · BALL STATE UNIVERSITY · PI KALINSKI, ASHLEY L, ROOSSIEN, DOUGLAS HOWARD · 2023 to 2023
$447k
NINDS NIH HHS R15 NS128837
6 · The paper itself

Abstract

SARM1 is a key executor of Wallerian degeneration in axons. Global knockout of

Indexed as

InflammationMacrophagesRegenerationSARM1Wallerian Degeneration

Identifiers

PMID41993406
PMCPMC13082023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.