Evidence map›Paper›PMID 41993199›Full record

ReviewFrontiers in immunology2026

Immune evasion, dysregulation, and emerging immunotherapies for invasive fungal infections in the immunocompromised host.

Haiying Liu, Chunyan Wang, Weijuan Huang, Shuhua Hu, Congfu Huang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haiying Liu *Department of Pediatrics, Shenzhen Maternity and Child Healthcare Hospital, Women and Children's Medical Center, Southern Medical University, Shenzhen, Guangdong, China.
Chunyan Wang *Department of Pediatrics, Shenzhen Fourth People's Hospital(Sami Medical Center), Shenzhen, Guangdong, China.
Weijuan Huang *Department of Pediatrics, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, Guangdong, China.
Shuhua HuDepartment of Pediatrics, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, Guangdong, China.
Congfu HuangDepartment of Pediatrics, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections (IFIs) represent a persistent challenge to global health, particularly in immunocompromised individuals, among whom they remain a leading cause of morbidity and mortality. Conventional antifungal regimens face growing limitations due to the emergence of drug resistance, drug-associated toxicities, and suboptimal efficacy. This review synthesizes advances from 2015 to 2025 in understanding the dynamic interactions between major fungal pathogens-

Indexed as

Immune EvasionImmunocompromised HostImmunotherapyInvasive Fungal InfectionsAnimalsAntifungal AgentsHost-Directed TherapyHost-Pathogen InteractionsHumansAntifungal AgentsCAR-T cellsimmune checkpoint inhibitorsimmune dysregulationimmune evasionimmunocompromised hostimmunotherapyinvasive fungal infectionsprecision medicine

Identifiers

PMID41993199
PMCPMC13079191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.